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Joint Research
Results (Published papers)
2025年度
Roux N.; Delannoy C.; Yu S.-Y.; Miura S.; Carlu L.; Besseau L.; Nakagawa T.; Sato C.; Kitajima K.; Guerardel Y.; Laudet V.
Anemonefish use sialic acid metabolism as Trojan horse to avoid giant sea anemone stinging
BMC Biology
https://doi.org/10.1186/s12915-025-02144-8
Ohno S.; Ogura C.; Yabuki A.; Itoh K.; Manabe N.; Angata K.; Togayachi A.; Aoki-Kinoshita K.; Furukawa J.-I.; Inamori K.-I.; Inokuchi J.-I.; Kaname T.; Nishihara S.; Yamaguchi Y.
VarMeter2: An enhanced structure-based method for predicting pathogenic missense variants through Mahalanobis distance
Computational and Structural Biotechnology Journal
Yamashita K.; Ito A.; Ishida M.; Shintani Y.; Ikeda M.; Hadano S.; Izumi M.; Ochi R.
Stereoisomerism-dependent gelation and crystal structures of glycosylated N-methylbromomaleimide-based supramolecular hydrogels
Soft Matter
Fujita M.
Maintenance of the Golgi ribbon structure by the KASH protein Jaw1
Journal of Biochemistry
Kurogochi M.; Suzuki C.; Hanamatsu H.; Furukawa J.-I.
Advances in total glycomic analysis including sialylated sub-glycan isomers by SALSA method
BBA Advances
Suzuki K.; Wu D.; Kitajima K.; Yamakawa N.; Omoto T.; Hane M.; Sato C.
Development of a permethylation-based detection method for oligo/polysialic acid structures via tandem MALDI-TOF mass spectrometry
BBA Advances
https://doi.org/10.1016/j.bbadva.2025.100155
Takahashi M.; Komura N.; Tanaka H.-N.; Imamura A.; Ishida H.; Ando H.
Ganglioside analog synthesis via late-stage sialylation and fatty acid introduction
Carbohydrate Research
Ohkawa M.; Kamata K.; Kawsar S.M.A.; Gerdol M.; Fujii Y.; Ozeki Y.
Characterization of HOL-30: a novel tandem-repeat galectin from the marine sponge Halichondria okadai
BBA Advances
Wang D.; Fukuda T.; Wu T.; Xu X.; Isaji T.; Gu J.
Exogenous L-fucose attenuates depression induced by chronic unpredictable stress: Implicating core fucosylation has an antidepressant potential
Journal of Biological Chemistry
Yamada K.
Minor acidic glycans: Review of focused glycomics methods
BBA Advances
Hanamatsu H.; Suda G.; Ohara M.; Ogawa K.; Tamaki N.; Hikita H.; Haga H.; Maekawa S.; Sugiyama M.; Kakisaka T.; Nakai M.; Sho T.; Miura N.; Kurosaki M.; Asahina Y.; Taketomi A.; Ueno Y.; Takehara T.; Nishikaze T.; Furukawa J.-I.; Sakamoto N.
Elevated A2F bisect N-glycans of serum IgA reflect progression of liver fibrosis in patients with MASLD
Journal of Gastroenterology
Cai Z.; Isaji T.; Liang C.; Fukuda T.; Zhang D.; Gu J.
Fucosyltransferase 4 upregulates P-gp expression for chemoresistance via NF-κB signaling pathway
Biochimica et Biophysica Acta – General Subjects
2024年度
Sun Y.; Xu X.; Wu T.; Fukuda T.; Isaji T.; Morii S.; Nakano M.; Gu J.
Core fucosylation within the Fc-FcγR degradation pathway promotes enhanced IgG levels via exogenous L-fucose
Journal of Biological Chemistry
Chythra J.N.; Guvench O.; MacKerell Jr A.D.; Yamaguchi T.; Mallajosyula S.S.
Refinement of the Drude Polarizable Force Field for Hexose Monosaccharides: Capturing Ring Conformational Dynamics with Enhanced Accuracy
Journal of Chemical Theory and Computation
https://doi.org/10.1021/acs.jctc.4c00656
Wu T.; Sun Y.; Wang D.; Isaji T.; Fukuda T.; Suzuki C.; Hanamatsu H.; Nishikaze T.; Tsumoto H.; Miura Y.; Furukawa J.-I.; Gu J.
The acetylglucosaminyltransferase GnT-Ⅲ regulates erythroid differentiation through ERK/MAPK signaling
Journal of Biological Chemistry
https://doi.org/10.1016/j.jbc.2024.108010
Hasnat M.A.; Ohmi Y.; Yesmin F.; Kambe M.; Kawamoto Y.; Bhuiyan R.H.; Mizutani M.; Hashimoto N.; Tsuchida A.; Ohkawa Y.; Kaneko K.; Tajima O.; Furukawa K.; Furukawa K.
Crucial roles of exosomes secreted from ganglioside GD3/GD2-positive glioma cells in enhancement of the malignant phenotypes and signals of GD3/GD2-negative glioma cells
Nagoya Journal of Medical Science
Hasnat M.A.; Ohmi Y.; Yesmin F.; Kaneko K.; Kambe M.; Kitaura Y.; Ito T.; Imao Y.; Kano K.; Mishiro-Sato E.; Koyanagi H.; Kawamoto Y.; Bhuiyan R.H.; Ohkawa Y.; Tajima O.; Furukawa K.; Furukawa K.
Action Mechanisms of Exosomes Derived from GD3/GD2-Positive Glioma Cells in the Regulation of Phenotypes and Intracellular Signaling: Roles of Integrins
International Journal of Molecular Sciences
Zhang Z.; Isaji T.; Oyama Y.; Liu J.; Xu Z.; Sun Y.; Fukuda T.; Lu H.; Gu J.
O-GlcNAcylation of Focal Adhesion Kinase Regulates Cell Adhesion, Migration, and Proliferation via the FAK/AKT Pathway
Biomolecules
Hayashi R.; Kamata K.; Gerdol M.; Fujii Y.; Hayashi T.; Onoda Y.; Kobayashi N.; Furushima S.; Ishiwata R.; Ohkawa M.; Masuda N.; Niimi Y.; Yamada M.; Adachi D.; Kawsar S.M.A.; Rajia S.; Hasan I.; Padma S.; Chatterjee B.P.; Ise Y.; Chida R.; Hasehira K.; Miyanishi N.; Kawasaki T.; Ogawa Y.; Fujita H.; Pallavicini A.; Ozeki Y.
Novel Galectins Purified from the Sponge Chondrilla australiensis: Unique Structural Features and Cytotoxic Effects on Colorectal Cancer Cells Mediated by TF-Antigen Binding
Marine Drugs
Tang Y.-H.; Leng J.-X.; Yang G.; Gao X.-D.; Liu Y.-S.; Fujita M.
Production of CA125 with Tn antigens using a glycosylphosphatidylinositol anchoring system
Journal of Biochemistry
Hanamatsu H.; Yokota I.; Kurogochi M.; Akasaka-Manya K.; Miura N.; Manya H.; Endo T.; Nishikaze T.; Furukawa J.-I.; Tanaka K.
Direct derivatization of sialic acids and mild β-elimination for linkage-specific sialyl O-glycan analysis
Analytica Chimica Acta
Fujii Y.; Kamata K.; Gerdol M.; Hasan I.; Rajia S.; Kawsar S.M.A.; Padma S.; Chatterjee B.P.; Ohkawa M.; Ishiwata R.; Yoshimoto S.; Yamada M.; Matsuzaki N.; Yamamoto K.; Niimi Y.; Miyanishi N.; Konno M.; Pallavicini A.; Kawasaki T.; Ogawa Y.; Ozeki Y.; Fujita H.
Multifunctional Cell Regulation Activities of the Mussel Lectin SeviL: Induction of Macrophage Polarization toward the M1 Functional Phenotype
Marine Drugs
Liu J.; Isaji T.; Komatsu S.; Sun Y.; Xu X.; Fukuda T.; Fujimura T.; Takahashi S.; Gu J.
BRCC36 associates with FLT3-ITD to regulate its protein stability and intracellular signaling in acute myeloid leukemia
Cancer Science
Kondo Y.; Li Y.; Okajima T.
Efficient Escorting Strategy for Aggregation-Prone Notch EGF Repeats with Sparcl1
Molecules
Isaji T.; Gu J.
Novel regulatory mechanisms of N-glycan sialylation: Implication of integrin and focal adhesion kinase in the regulation
Biochimica et Biophysica Acta – General Subjects
Xu X.; Fukuda T.; Takai J.; Morii S.; Sun Y.; Liu J.; Ohno S.; Isaji T.; Yamaguchi Y.; Nakano M.; Moriguchi T.; Gu J.
Exogenous L-fucose attenuates neuroinflammation induced by lipopolysaccharide
Journal of Biological Chemistry
2023年度
Sugiura K, Kawai Y, Yamamoto A, Yoshioka H, Kiyohara Y, Iida A, Ozawa Y, Nishikawa M, Miura N, Hanamatsu H, Furukawa JI, Shinohara Y.
Exposure to brefeldin A induces unusual expression of hybrid- and complex-type free N-glycans in HepG2 cells
Biochimica et Biophysica Acta – General Subjects
Song W, Liang C, Sun Y, Morii S, Yomogida S, Isaji T, Fukuda T, Hang Q, Hara A, Nakano M, Gu J.
Expression of GnT-III decreases chemoresistance via negatively regulating P-glycoprotein expression: Involvement of the TNFR2-NF-κB signaling pathway
J.Biol. Chem.